What are the limitations?
Traditional liquid chromatography (LC) separation and detector strategies are restricted in the variety of organic solvents that can be used because of the inherent organic chromophore competition for UV absorption at […]
The pharmaceutical industry's stringent regulations require researchers and engineers to go above and beyond to ensure products' safety and quality. Whether the goal is in-process preparative separation, or to purify pharmaceutical ingredients […]
Did your 2020 goals go as planned? We bet they didn’t! This year and its many turns affected the schedule of most industries and shifted public interest towards the scientific community. Despite the current global health crisis, research […]
UV inactivation is increasingly gaining traction among laboratories and manufacturers as a disinfection and decontamination solution. It is a clean and rapid method for either elimination of contaminants or preparation of viruses for vaccine […]
As in many other scientific applications, photochemical reactions face challenges when scaling up to industrial volume and performance. Maximizing resources in this industry is a must while ensuring the highest quality and purification standards. […]
Choosing a detector for your preparative chromatography set up can be overwhelming in a crowded market. So here are some factors to take into account when looking for a detector to suit your laboratory's needs:
“Cash is king” they say, and one could argue, it is one of the dirtiest kings out there. Research on the contamination burden of currency points to the benefits of a cashless society, and whether this solution may seem constrictive, imperative, […]
UV LED light has proven to be effective in laboratory settings for disinfection and decontamination purposes, making these processes cheaper, faster, and more reliable. UV LED has now revolutionized large laboratories and institutions, however […]
UV LED radiation has proven to be an effective and innovative measure for disinfection and decontamination. Particular wavelengths affect different bonds within biological molecules. Therefore, determining what wavelengths are most effective […]
On our previous episode of the Keylight Series, we highlighted its compact design for easy integration, its availability for customizable features and IR sources, as well as Phoseon's patented technology. Today, we'll talk about 4 features that […]
Microscopy has been around for centuries and represents one of the greatest advances in the scientific community. The development of its fluorescent counterpart in the 20th century and recent break-throughs in this field have taken medicine and […]
Great news appear in the Covid-19 prevention research landscape! Recent studies from Boston University have concluded 22 mJ/cm2 of UVC light should be enough dose to approach 6 log reduction of the Sars-CoV-2 virus (also known as corona-virus) […]
Previous research has shown that KeyProTM (Phoseon Technology) rapidly and reliably decontaminates laboratory pipetman (1, 2). The unanswered question is, how necessary is this decontamination? Here we present a quantification of the […]
What is currently being used?
Current procedures for vaccine research often utilize gamma radiation to inactivate a virus while leaving host protein structures intact for further analysis like ELISAs. Unfortunately, gamma radiation technology is […]
Certainly so! The principle behind vaccinations is to trigger an immune response that will provide us with antibodies to prevent infection in the future. This goal can be accomplished through a variety of mechanisms that are encompassed in 4 […]
ConclusionThe KeyView Prep™ system allows for real-time 260/280 analysis that is both efficient and accurate.IntroductionSince its conception in the 1940s, the 260/280 assessment of nucleic acid purity has routinely relied on spectrophotometric […]
In this study, UV LEDs were used to excite tissue auto-fluorescence
RNA library prep, sequencing, and PCR
RNase A Contamination: Unpredictable and Catastrophic
Presented at the International Association of Food Protection
Known as a pioneer in UV LED solutions, Phoseon’s focus on customer collaboration has resulted in a world-wide market leadership position.
Working from previous knowledge that 275nm and 365nm sources work synergistically to speed RNase A inactivation, we used these wavelengths on Greiner Bio-One flat-bottomed black opaque microplates. Sample wells were first treated with 0.01u/mL of […]
RNase A Activity as a Predictive Tool for Log₁₀ Reduction of Bacterial and Fungal Spores on Surfaces
Certain clinically relevant organisms, such as Clostridium difficile (Clostridioides difficile) and Aspergillus brasilliensis, form spores that are resistant to UV inactivation. Indeed, Log₁₀ reduction in response to UV exposure is dependent not […]
Many experiments are carried out in Tris buffers because they are nearly bulletproof at maintaining a neutral pH regardless of what you (metabolically) throw at them. These buffers cannot be subjected to the same decontamination methods, as DEPC […]